Acoustofluidics

YouTube acoustofluidics movie  "Diving with microparticles in acoustic fields"
presented at the APS Annual Meeting 2012 and in Phys. Rev. E (pdf)
 

Publications

Peer-reviewed journal papers
PhD theses
MSc theses

BSc theses

Current postdocs and students

Massimiliano Rossi (Associate professor)
Wei Qiu (Visiting postdoc)
Jacob Søberg Bach (PhD student)
André G. Steckel (PhD student)
Jonas H. Jørgensen (PhD student)
William Naundrup Bodé (PhD student)
Fabian Lickert (PhD student)
Bjørn G. Winckelmann (MSc student)
Søren Kuhberg (BSc student) 


Peer-reviewed journal papers


2020

Microparticle acoustophoresis in
aluminum-based acoustofluidic devices with PDMS covers

W.N. Bodé, L. Jiang, T. Laurell, and H. Bruus
Micromachines 11, 292 1-15 (2020).  (pdf
  

2019
Theory of acoustic trapping of microparticles in capillary tubes

J. S. Bach and H. Bruus
Phys. Rev. E 101, 023107 1-12 (2020).  (pdf)

Three-dimensional numerical modeling of surface-acoustic-wave devices:
Acoustophoresis of micro- and nanoparticles including streaming 
 
N.R. Skov, P. Sehgal, B.J. Kirby, and H. Bruus
Phys. Rev. Appl., 12, 044028 1-17 (2019).  (pdf)

Bulk-driven acoustic streaming at resonance in closed microcavities  
J. S. Bach and H. Bruus
Phys. Rev. E, 100, 023104 1-20 (2019).  (pdf)

The 2019 surface acoustic waves roadmap  
P Delsing, A N Cleland, M J A Schuetz, J Knörzer , G Giedke , J I Cirac, K Srinivasan, M Wu, K Balram,  C Bäuerle, T Meunier, C J B Ford, P V Santos, E Cerda-Méndez, H Wang, H J Krenner, E D S Nysten, M Weiss, G R Nash, L Thevenard, C Gourdon, P Rovillain, M Marangolo, J-Y Duquesne, G Fischerauer, W Ruile, A Reiner, B Paschke, D Denysenko, D Volkmer, A Wixforth, H Bruus, M Wiklund, J Reboud, J M Cooper, Y Q Fu, M S Brugger, F Rehfeldt, and C Westerhausen
J. Phys. D: Appl. Phys. 52, 353001 1-40 (2019).  (pdf)

Two-dimensional mapping separating the acoustic radiation force and streaming in microfluidics  
S. Liu, Z. Ni, G. Xu, X. Guo, J.  Tu, H. Bruus, and D. Zhang
Phys. Rev. Appl., 11, 044031 1-10 (2019).  (pdf)

Characterization of acoustic streaming in gradients of density and compressibility 
W. Qiu, J. T. Karlsen, H. Bruus, and P. Augustsson
Phys. Rev. Appl., 11, 024018 1-11 (2019).  (pdf)
 
3D modeling of acoustofluidics in a liquid-filled cavity including streaming, viscous boundary layers, surrounding solids, and a piezoelectric transducer  
N.R. Skov, J.S. Bach, B.G. Winckelmann, and H. Bruus
AIMS Math 4, 99-111 (2019).  (pdf)
 
Whole-system ultrasound resonances as the basis for acoustophoresis in all-polymer microfluidic devices   
R.P. Moiseyenko and H. Bruus
Phys. Rev. Appl. 11, 014014 1-14 (2019).  (pdf)

2018
Theory of pressure acoustics with viscous boundary layers
and streaming in curved elastic cavities
 
  
J. S. Bach and H. Bruus
J. Acoust. Soc. Amer. 144, 766-784 (2018).  (pdf)
 
Intra-droplet acoustic particle focusing:
simulations and experimental observations
 
  
A. Fornell, F. Garofalo,  J. Nilsson, H. Bruus, and M. Tenje
Microfluid Nanofluid 22, 75 1-9 (2018).  (pdf)
 
Acoustic streaming and its suppression in inhomogeneous fluids   
J.T. Karlsen, W. Qiu, P. Augustsson, and H. Bruus
Phys. Rev. Lett. 120, 054501 1-6 (2018).  (pdf)

2017
Three-dimensional numerical modeling of acoustic trapping in glass capillaries   
M.W.H. Ley and H. Bruus
Phys. Rev. Appl. 8, 204020 1-15 (2017).  (pdf

Ultrasound characterization of microbead and cell suspensions
by speed of sound measurements of neutrally buoyant samples
 
  
K. Cushing, F. Garofalo, C. Magnusson, L. Ekblad, H. Bruus, T. Laurell
Analytical Chem., 89, 8917-8923 (2017).  (pdf
 
Ultrasound rays in droplets:
the role of viscosity and caustics in acoustic streaming
 
 
H. Bruus
J. Fluid Mech. 826, 1-4 (2017).  (pdf

Improved positioning and detectability of microparticles
in droplet microfluidics using two-dimensional acoustophoresis
 
M. Ohlin, A. Fornell, H. Bruus, and M. Tenje
J. Micromech. Microeng. 27, 084002 1-8 (2017).  (pdf

Acoustic tweezing and patterning of concentration fields in microfluidics  
J. T. Karlsen and H. Bruus
Phys. Rev. Appl. 7, 034017 1-10 (2017).  (pdf
 
Performance study of acoustophoretic microfluidic silicon-glass devices by
characterization of material- and geometry-dependent frequency spectra
 
F. Garofalo, T. Laurell, and H. Bruus
Phys. Rev. Appl. 7, 054026 1-16 (2017).  (pdf


 
Modeling of microdevices for SAW-based acoustophoresis 
– a study of boundary conditions
 
N. R. Skov and H. Bruus
Micromachines 7, 182 1-14 (2016).  (pdf
 
Acoustic force density acting on inhomogeneous fluids in acoustic fields
J. T. Karlsen, P. Augustsson, and H. Bruus
Phys. Rev. Lett. 117, 114504 (2016).  (pdf
 
Iso-acoustic focusing of cells for size-insensitive acousto-mechanical phenotyping
P. Augustsson, Jonas T. Karlsen, H.-W. Su, H. Bruus, and J. Voldman
Nat Commun 7, 11556 1-9 (2016). (pdf
 
Continuum modeling of hydrodynamic particle-particle interactions
in microfluidic high-concentration suspensions

M.W.H. Ley and H. Bruus 
Lab Chip 16, 1178-1188 (2016). (pdf
  
A theoretical study of time-dependent, ultrasound-induced
acoustic streaming in microchannels

P.B. Muller and H. Bruus
Phys. Rev. E 92, 063018 1-13 (2015). (pdf
 
Forces acting on a small particle in an acoustical field in a thermoviscous fluid
J.T. Karlsen and H. Bruus
Phys. Rev. E 92, 043010 1-22 (2015). (pdf
 
Acoustic interaction forces between small particles in an ideal fluid
G.T. Silva and H. Bruus
Phys. Rev. E 90, 063007 1-11 (2014). (pdf)

A numerical study of thermoviscous effects in ultrasound-induced
acoustic streaming in microchannels

P.B. Muller and H. Bruus
Phys. Rev. E 90, 043016 1-12 (2014). (pdf
  
Focusing of sub-micrometer particles and bacteria
enabled by two-dimensional acoustophoresis

M. Antfolk, P.B. Muller, P. Augustsson, H. Bruus, and T. Laurell.
Lab Chip 14, 2791-2799 (2014). (pdf)
 
Tunable-angle wedge transducer for improved
acoustophoretic control in a microfluidic chip

I. Iranmanesh, R. Barnkob, H. Bruus, and M. Wiklund 
J. Micromech. Microeng. 23, 105002 1-10 (2013). (pdf) 
 
Ultrasound-induced acoustophoretic motion of microparticles in three dimensions
P.B. Muller, M. Rossi, A. G. Marin, R. Barnkob,
P. Augustsson, T. Laurell, C. J. Kähler, and H. Bruus
Ultrasound-induced acoustophoretic motion of microparticles in three dimensions
Phys. Rev. E 88, 023006 1-12 (2013). (pdf) 
 
Acoustic radiation- and streaming-induced microparticle velocities
determined by micro-PIV in an ultrasound symmetry plane

R. Barnkob, P. Augustsson, T. Laurell, and H. Bruus
Phys. Rev. E 86, 056307 1-11 (2012). (pdf) 
 
A numerical study of microparticle acoustophoresis driven by
acoustic radiation forces and streaming-induced drag forces

P.B. Muller, R. Barnkob, M.J.H. Jensen, and H. Bruus
Lab Chip 12, 4617-4627 (2012). (pdf)
   
High-throughput temperature-controlled microchannel
acoustophoresis device made with rapid prototyping

J.D. Adams, C.L. Ebbesen, R. Barnkob, A.H.J. Yang, H.T. Soh, and H. Bruus
J Micromech Microeng 22, 075017 (2012). (pdf)
 
Measuring acoustic energy density in microchannel acoustophoresis
using a simple and rapid light-intensity method

R. Barnkob, I. Iranmanesh, M. Wiklund, and H. Bruus.
Lab Chip 12, 2337-2344 (2012). (pdf)
 
Forces acting on a small particle in an acoustical field in a viscous fluid
M. Settnes and H. Bruus
Phys. Rev. E 85, 016327 1-12 (2012). (pdf)
 
Acoustofluidics 10: Scaling laws in acoustophoresis
H. Bruus
Lab Chip 12, 1578-1586 (2012). (pdf)
  
Acoustofluidics 7: The acoustic radiation force on small particles
H. Bruus.
Lab Chip 12, 1014-1021 (2012). (pdf)
   
Acoustofluidics 2: Perturbation theory and ultrasound resonance modes
H. Bruus
Lab Chip 12, 20-28 (2012). (pdf)
 
Acoustofluidics 1: Governing equations in microfluidics
H. Bruus
Lab Chip 11, 3742-3751 (2011). (pdf)
 
Forthcoming Lab on a Chip tutorial series on acoustofluidics:
Acoustofluidics—exploiting ultrasonic standing wave forces and
acoustic streaming in microfluidic systems for cell and
particle manipulation

H. Bruus, J. Dual, J. Hawkes, M. Hill, T. Laurell, J. Nilsson,
S. Radel, S.S. Sadhal, and M. Wiklund
Lab Chip 11, 3579-3580 (2011). (pdf)
 
Automated and temperature-controlled micro-PIV measurements
enabling
long-term-stable microchannel acoustophoresis characterization

P. Augustsson, R. Barnkob, S.T. Wereley, H. Bruus, and T. Laurell
Lab Chip 11, 4152–4164 (2011). (pdf)
 
Acoustophoretic synchronization of mammalian cells in microchannels
P. Thevoz, J.D. Adams, H. Shea, H. Bruus, and H.T. Soh
Anal. Chem. 82, 3094-3098 (2010) (pdf)
 
Measuring the local pressure amplitude in microchannel acoustophoresis
R. Barnkob, P. Augustsson, T. Laurell, and H. Bruus
Lab Chip 10, 563-570 (2010) (pdf)
 
Integrated acoustic and magnetic separation in microfluidic channels
J.D. Adams, P. Thevoz, H. Bruus, and H.T. Soh
Appl. Phys. Lett. 95, 254103 1-3 (2009) (pdf)
 
Selective bioparticle retention and characterization
in a chip-integrated confocal ultrasonic cavity

J. Svennebring, O. Manneberg, P. Skafte-Pedersen, H. Bruus, and M. Wiklund
Biotechnol. Bioeng. 103, 323-328 (2009) (pdf)
 
Spatial confinement of ultrasonic force fields in microfluidic channels
O. Manneberg, S.M. Hagsäter, J. Svennebring, H.M. Hertz,
J.P. Kutter, H. Bruus, and M. Wiklund
Ultrasonics 49, 112-119 (2009) (pdf)
 
Acoustic resonances in straight micro channels:
Beyond the 1D-approximation

S.M. Hagsäter, A. Lenshof, P. Skafte-Pedersen,
J.P. Kutter, T. Laurell, and H. Bruus
Lab Chip 8, 1178-1184 (2008) (pdf)
 
Acoustic resonances in piezo-actuated microfluidic chips:
full-image micro-PIV experiments and numerical simulations

S. M. Hagsäter, T.G. Jensen, H. Bruus and J.P. Kutter
Lab Chip 7, 1336-1344 (2007) (pdf)

 

PhD theses

Modeling of complex acoustofluidic devices
Nils R. Skov
(June 2019, 179 pages, pdf)

Theory of nonlinear acoustic forces acting
on fluids and particles in microsystems
Jonas T. Karlsen
(January 2018, 174 pages, pdf)
 
Effective modelling of acoustofluidic devices
Mikkel Wennemoes Hvitfeld Ley
(August 2017, 141 pages, pdf)
 
Acoustic streaming in microchannels:
the trinity of analytics, numerics and experiments
Peter Muller Tribler (né Barkholt Muller)
(September 2015, 148 pages, pdf 
 
Physics of microparticle acoustophoresis
- bridging theory and experiment

Rune Barnkob
(August 2012, 214 pages, pdf)
 

MSc theses

Acoustic streaming in polymer systems  
William Naundrup Bodé
(June 2019, 98 pages, pdf)
 
Theory and simulation of the acoustic radiation force
on a suspended microparticlemodelling
 

Nicolas Vauchel
(September 2017, 32 pages, pdf)
 
Theory and simulation of microscale acoustic streaming
in three dimensions: a study in effective modelling

Jacob Søberg Bach
(January 2017, 110 pages, pdf)

Surface acoustic waves in microfluidic devices: simulation and instrumentation
Nils Refstrup Skov
(March 2016, 101 pages, pdf

Theory and finite-element modeling of electrokinetics  in microchannels with permselective elements
Rasmus Dybbro Engelsholm
(October 2014, 96 pages, pdf

Theory of thermoviscous acoustofluidics in microsystems
Jonas T. Karlsen
(March 2014, 130 pages, pdf
 
Hydrodynamics interactions in microfluidic acoustophoresis
Mikkel W. H. Ley
(February 2014, 102 pages, pdf)  
 
Acoustofluidics in microsystems: investigation of acoustic streaming
Peter Barkholt Muller
(March 2012, 101 pages, pdf
 
Theory and application of ultrasound diagnostics of aqueous solutions
Kasper Kristensen 
(July 2010, 122 pages, pdf)  
 
Acoustofluidics in microsystems: investigation of resonances
Rune Barnkob
(June 2009, 138 pages, pdf
 
Acoustic forces on particles and liquids in microfluidic systems
Peder Skafte-Pedersen 
(January 2008, 183 pages, pdf
 
Acoustic radiation in microfluidic systems
Thomas Glasdam Jensen
(April 2007, 117 pages, pdf
 
 

BSc theses

Piezoelectric actuation of acoustophoretic systems   
Bjørn G. Winckelmann
(June 2018, 62 pages, pdf
 
Theory and numerical modeling of microscale acoustofluidics   
William Frisch Møller
(June 2017, 62 pages, pdf
 
Theory and numerical modeling of all-polymer based acoustofluidic devices   
William N. Bodé and Thor H. Snedker
(June 2017, 97 pages, pdf
 
Theory of microscale acoustofluidics in inhomogeneous suspensions   
Jakob Milo Hauge
(July 2016, 103 pages, pdf)

Acoustic levitation of particles
Andreas Muff Munk
(June 2016, 87 pages, pdf

 
Temperature-controlled, high-throughput acoustophoretic
particle separation in microchannels

Christian Laut Ebbesen 
(June 2010, 71 pages, pdf
 
Forces acting on microparticles in acoustofluidic systems
Lasse Mejling Andersen, Anders Nysteen, and Mikkel Settnes 
(June 2009, 167 pages, pdf)
 
Theoretical acoustofluidics in microsystems: Theory and simulation
Torben Nielsen and Alan Wiinberg 
(June 2008, 105 pages, pdf)
 
Theoretical acoustofluidics in microsystems
Sofie Sabine Rose Moth and Julie Refsgaard Lawaetz  
(June 2007, 125 pages, pdf

https://www.staff.dtu.dk/bruus/Researchtopics/Acoustofluidics.aspx
7 MARCH 2021